Our new Crystal clear+ tissue clearing strategy is the sole method that delipidates samples without having adjust in morphology and with minimum impact on structural integrity.
Our flip-vital SmartBatch+ program combines electrophoretic tissue clearing and immunolabeling into just one large-throughput machine.
Antibodies might choose weeks to diffuse as a result of only a few millimeters of tissue, which has a steep labeling gradient from surface area to Main.
Megatome is made for precision: the blade vibrates at a greater frequency and bigger amplitude variety than other microtomes, and contains a distinctive deflection Management mechanism.
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Our preformulated EasyIndex Resolution raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely transparent. This enables mild penetration in the sample and makes sure the acquisition of higher-resolution, in-target impression facts.
Megatome is really a novel microtome that permits for high-precision sectioning of an array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with minimum tissue injury and data reduction.
eFLASH is actually a megatomi.com speedy tissue labeling strategy that permits for uniform complete-organ staining in 20 rounds of labeling.
Absolutely delipidate total mouse brains or comparably sized samples in only one day with SmartBatch+, or in one 7 days with our passive clearing package.
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Protect avoids the variability of hydrogel embedding and the knowledge loss from PFA preservation, preserving specimens for a number of rounds of processing.
Leverage the Very clear+ tissue clearing method, as well as eFLASH and patented stochastic electrotransport technologies, to speedily distinct and label total organs. Important highlights and capabilities consist of:
Our novel Protect tissue preservation approach sorts intramolecular bonds utilizing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.